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Dissemination & Implementation Research Core (DIRC)

The Dissemination and Implementation Research Core (DIRC) provides methodological expertise to advance translational research that moves efficacious health practices from clinical knowledge into routine, real-world use—a process called Dissemination and Implementation research (DIRC). The DIRC focuses on the second of two areas of translational research, as defined by NIH: research to inform the adoption of best practices in the community.  

The DIRC is led by researchers from WU’s Schools of Social Work and Medicine, and the Institute for Public Health lead and service the Core—Enola Proctor, PhD, PI; Ross Brownson, PhD; Graham Colditz, MD, DrPH, FAFPHM; and Doug Luke, PhD. The Core leadership work to expand multidisciplinary groups around shared expertise and interest in Translation Two (T2), and launch plans for long-term self-sustainability through a growing “customer” base of externally funded investigators with whom DIRC participants will collaborate on future research grants.    

Complementing existing ICTS Cores, the DIRC has three aims that lead to developing and making available specific research tools required for studying the D& I of health care discoveries: 

  • To develop collaborations among ICTS investigators and related faculty with the distinct expertise required for dissemination and implementation research, and coalesce that expertise in the new DIRC. 
  • To launch the DIRC by building specific research-enhancing services, tools, measures, and by supporting ICTS investigators who wish to conduct Translation Two (T2) research. Services include a) A seminar series and glossaries of terminology key to D&I research; b) A database of D&I researchers conducting federally funded T2 research and a current listing of grant PA’s and RAF’s from NIH, CDC, AHCPR, and such foundations as Robert Woods Johnson supporting T2 research; c) Measures for evaluating process and structural outcomes of the dissemination and implementation process and to test their relationship to ultimate clinical outcomes; d) A repertoire of evidence-based dissemination and implementation strategies, e) Design expertise for the unique challenges of T2 research (multiple levels of analysis, multiple stakeholders, and power limitations for within-organizational research); and f) A laboratory for modeling change through systems dynamics modeling.  
  • To develop sustainability of the DIRC, thus extending to ICTS investigators D & I collaboration, support, and mentoring. The D & I Core will advance T2 research in the WU ICTS by increasing the number and quality of research projects that are equipped to address scientific questions about how to disseminate and implement new health care practices in real-world community-based health care settings. 

The DIRC will meet NIH criteria to: develop collaboration between departments and schools; provide the translational technologies and knowledge base for the spectrum of clinical and translational science, complement and interact with existing centers that are funded by the NIH; and advance clinical and translational science as a distinct discipline by developing research-enhancing services, tools, and measures for the use of investigators who want to conduct T2 research.

This initiative is made possible by Grant Number UL1 RR024992 from the National Center for Research Resources (NCRR), a component of the National Institutes of Health (NIH) and NIH Roadmap for Medical Research.   

Supported by Clinical and Translational Science Award (CTSA) program of the National Center for the Research Resources (NCRR) at the National Institutes of Health (NIH) Grant  Number UL1 RR024992

For any questions, please email us: DIRC@wustl.edu

DIRC services are targeted to ICTS members. To become an ICTS member, register here

ICTS DIRC website: http://icts.wustl.edu/cores/dirc.aspx
Read more about the DIRC in the most recent edition of the Institute of Clinical and Translational Sciences newsletter: http://icts.wustl.edu/about/Feb10ICTSNews.pdf